Top Document: diabetes FAQ: treatment (part 3 of 5) Previous Document: What claims do the sales pitches make for pycnogenol? Next Document: How reliable is the literature cited by the pycnogenol ads? See reader questions & answers on this topic! - Help others by sharing your knowledge Written by Laura Clift. (refs) point to "pycnogenol references" section. In a study examining the anti-oxidant action of several bioflavanoids, (-)-epicatechin 3-O-gallate and (-)-epigallocatechin 3-O-gallate were both more potent than pycnogenol against the free radicals DPPH, superoxide anion, OH, and OOH, although not by much (1). The toxicity of pycnogenol is not established in published reports. Proanthocyanidin mutagenicity is tricky, if it is completely pure it is considered non-mutagenic. However, there is an impurity that is very similar and hard to remove in the purification of proanthocyanidin that is mutagenic (2). No published work could be found on the bioavailability of pycnogenol in particular, but oral ingestion of bioflavanoids in general results in a low bioavailability (3). Pycnogenol does cross the blood-brain barrier in rats when given as an intraperitoneal injection (4). The same study seems to indicate that pycnogenol can increase capillary resistance and decrease capillary permeability in rats. A clinical study on 25 patients indicated an increase in capillary resistance (5). When administered by intraperitoneal injection to rats, chemically induced edema of the paw was decreased (6). There are no published studies on pycnogenol's interaction with vitamin C and most of the preventions, aids and/or cures claimed. However, procyanidol oligomers offered no protection for venous disease from hypoxia (lack of oxygen) (7). User Contributions:Comment about this article, ask questions, or add new information about this topic:Top Document: diabetes FAQ: treatment (part 3 of 5) Previous Document: What claims do the sales pitches make for pycnogenol? Next Document: How reliable is the literature cited by the pycnogenol ads? Part1 - Part2 - Part3 - Part4 - Part5 - Single Page [ Usenet FAQs | Web FAQs | Documents | RFC Index ] Send corrections/additions to the FAQ Maintainer: edward@paleo.org
Last Update March 27 2014 @ 02:11 PM
|
between and mg/dl and mmol/l is, i came across your article and was so pleased to aquire a lot more info regarding blood glucose, how to read and convert it.